14 Nov Photosensitive systemic lupus erythematosus (SLE) rashes typically occur on the face or extremities, which are sun-exposed regions. Although. 4 days ago Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation in connective tissues, such as cartilage and the lining of. Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of.

Author: Arakree Faujar
Country: Bahamas
Language: English (Spanish)
Genre: Environment
Published (Last): 2 August 2009
Pages: 27
PDF File Size: 10.26 Mb
ePub File Size: 3.81 Mb
ISBN: 941-5-14173-667-3
Downloads: 27279
Price: Free* [*Free Regsitration Required]
Uploader: Narisar

SLE has a modest recurrence rate in families: Other oral manifestations include dryness as a result of secondary Sjogren’s syndrome, and these patients also experience dryness of the eyes and vagina. The bimodal sistemik lupus eritematosus pattern of systemic lupus erythematosus.

Systemic lupus erythematosus

Although the specific cause of SLE is unknown, multiple genetic predispositions and gene-environment interactions have been identified see the chart in the image below. Convincing history of pleuritic pain or rub heard by a physician or evidence of pleural effusion or B Pericarditis: Other medications help control pain, including nonsteroidal anti-inflammatory drugs NSAIDs like ibuprofen or naproxen. The 19th century’s research into lupus continued with the work of Sir William Osler who, inpublished the first of his three papers about the internal complications of erythema exudativum multiforme.

Am J Clin Exp Sistemik lupus eritematosus. In addition, antibodies formed in the mother that are transferred from mother to fetus can occasionally affect the infant, leading to rashes, low blood counts, or more seriously a slow heart rate due to complete heart block neonatal sistemik lupus eritematosus.


Environmental and exposure-related causes of SLE are sistemik lupus eritematosus clear. Systemic lupus sisteimk optic neuritis: Cyclophosphamide, methotrexate, azathioprine, mycophenolate, cyclosporine.

The specific cause of SLE is not known. D ICD – Ir J Med Sci. Swelling in the legs Some people have only sistemik lupus eritematosus symptoms. Retrieved 7 June When is Binge Eating a Disorder?

Photo courtesy of Dr. SLE can affect any organ system, but it mainly involves the skin, joints, kidneys, blood cells, and nervous system see Presentation.

The Language of Medicine. Archived from the original on August 3, Spectrum of cardiac involvement in neonatal lupus.

Systemic lupus erythematosus – Wikipedia

Patients may present with any of the following manifestations [ 4 ]:. The neoclassical period began in when the skin disease which is now known as discoid sistemik lupus eritematosus was documented by the French physician, Pierre Cazenave.

Foods to Help You Concentrate. Epstein-Barr virus induces normal B cell responses sistemik lupus eritematosus defective suppressor T cell responses eriteematosus patients with systemic lupus erythematosus. How Much is Enough? This material may present sistemik lupus eritematosus threat to the tolerization of B cells and T cells. This is called a ” flu -like syndrome. Antibodies are proteins that normally help protect sritematosus body from lupue, like viruses and bacteria.


The immune system normally fights off dangerous infections and bacteria to keep the body healthy. Most patients will require treatment with corticosteroids prednisone to control the inflammation.

For other uses, see Lupus sistemik lupus eritematosus and SLE disambiguation. Keep in mind that not all patients suspected of having lupus meet these criteria. Readers Comments 20 Share Your Story. Some patients with lupus have very mild disease, which can be treated with simple medications, whereas others can have serious, life-threatening complications.

Systemic Lupus Erythematosus Causes, Treatment & Diagnosis

Dendritic cells in the germinal center may endocytose such antigenic material and erifematosus it to Sistemik lupus eritematosus cells, activating them. More than 90 percent of those affected will experience joint or muscle pain at some time during the course of their illness. Retrieved 6 May Archived sistemik lupus eritematosus the original on April 27, Wallace D, Edmund D, eds.

Although pleuritic symptoms may relate directly to active lupus, pulmonary embolism must always be considered, particularly in those who have antiphospholipid antibodies.

Autoreactive B cells, maturated coincidentally, normally do not receive survival signals by antigen planted on follicular dendritic cells and perish by apoptosis.

Possible early-life risk factors include the following [ 34 ]:.